S19. Summary

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S19-01 Planarians, stem cells, and regeneration

ical role in regulating their entry into the myogenic programme. We had shown that in the Pax3/7 double mutant the myogenic determination genes, Myf5 and MyoD are not activated, leading to a major deficit in skeletal muscle. Pax3 directly activates Myf5, thus promoting a myogenic cell fate. However, it is essential to maintain a balance between differentiation and renewal of the progenitor cell...

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ژورنال

عنوان ژورنال: Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics

سال: 2011

ISSN: 1882-8272,0388-1601

DOI: 10.3999/jscpt.42.183